Two sample MR report
NEBL_Monocyte (Mono) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0086434 | 0.5297801 | 0.9896144 |
| Weighted median | 3 | 0.0432786 | 0.0259424 | 0.0952643 |
| Inverse variance weighted | 3 | 0.0435106 | 0.0217987 | 0.0459317 |
| Simple mode | 3 | 0.0429847 | 0.0295896 | 0.2834658 |
| Weighted mode | 3 | 0.0428311 | 0.0315676 | 0.3076909 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0082029 | 1 | 0.9278342 |
| Inverse variance weighted | 0.0125418 | 2 | 0.9937487 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0467875 | 0.7102968 | 0.9581261 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.3e-05 | 0 | TRUE | 0.6491507 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
